Clozapine and the Treatment of Schizophrenia Essay -- Biological Psych

clozapine and the Treatment of schizophreniaclozapine, marketed by the passel name of Clozaril, is a member of the dibenzodiazepine class of antipsychotic medication, and is iodine of legion(predicate) types of antipsychotic agent doses. Clozapine is an abnormal medication because it differs from the older conventional drugs such as Halodol or Lithium. The difference between atypical and the older drugs is because in that location less neuroleptic action mechanism as a result of more(prenominal) specific receptors utilized. The atypical drugs work impressively to treat psychotic illnesses and course to have less positioning effects than their predecessors. Clozapine has been found to be the nearly effective antipsychotic drug for treatment resistant schizophrenia. Clozapine is utilise on a limited basis because of the risk of agranullocytosis, where blanched blood cells be destroyed faster than they are produced, causing the item-by-item to be given over to othe r illnesses. Two other drugs, either unitary typical and one atypical, or two atypical medications are used and deemed ineffective onwards clozapine is used due to the this serious side effect, agranullocytosis. Even sight this risk happens to be small, 1% to 2%, the drug is normally viewed in the psychiatric field as a method acting of last resort.(Kentridge, 1995)The most common explanation for what occurs in the brain of a schizophrenic is the dopamine hypothesis, where true areas of the brain have excessive activity at certain dopamine receptors.(Kalat, 2004) This theory will be a reoccurring theme when explaining how clozapine interacts with the body. There are also explanations dealing with clozapines fundamental interaction with the serotonin 5HT2 receptors and the glutamate receptors. ... ...hin a week levels will increase with treatment of colazopine.(Naheed & Green, 2000) Andreasen, N.C. (1994). dementia praecox From Mind to Molecule. Washington, DC America n Psychiatric Press.Kalat, J. (2004). Biological Psychology. 8Th edition, Chapter 15.3.Kentridge, B. (1995). S2 psychopathology Lecture 3 Schizophrenia. Retrieved bump into 4, 2005. From Http//www.dur.ac.uk/robert.kentridge/ppath3.htmlMann, R. (1996). The Role of Dopamine Receptors in Schizophrenia. Retrieved March 3, 2005, From Stanford University, Chemistry section web site, http//www.chem.csustan.edu/chem44x0/SJBR/Mann.htmNaheed, M., & Green, B. (2000). Focus on Clozapine. Retrieved February 7, 2005. From http//www.priory.com/focus14.htmWaddinton, J.L., & Buckley, P.F. (1996). The neurodevelopmental Basis of Schizophrenia. Austin, TX Landes Co. Clozapine and the Treatment of Schizophrenia Essay -- Biological PsychClozapine and the Treatment of SchizophreniaClozapine, marketed by the trade name of Clozaril, is a member of the dibenzodiazepine class of antipsychotic medication, and is one of many types of neuroleptic drugs. Clozapine is an atypical medication bec ause it differs from the older conventional drugs such as Halodol or Lithium. The difference between atypical and the older drugs is because there less neuroleptic activity as a result of more specific receptors utilized. The atypical drugs work effectively to treat psychotic illnesses and tend to have fewer side effects than their predecessors. Clozapine has been found to be the most effective antipsychotic drug for treatment resistant schizophrenia. Clozapine is used on a limited basis because of the risk of agranullocytosis, where white blood cells are destroyed faster than they are produced, causing the individual to be prone to other illnesses. Two other drugs, either one typical and one atypical, or two atypical medications are used and deemed ineffective before clozapine is used due to the this serious side effect, agranullocytosis. Even thought this risk happens to be small, 1% to 2%, the drug is normally viewed in the psychiatric field as a method of last resort.(Kentri dge, 1995)The most common explanation for what occurs in the brain of a schizophrenic is the dopamine hypothesis, where certain areas of the brain have excessive activity at certain dopamine receptors.(Kalat, 2004) This theory will be a reoccurring theme when explaining how clozapine interacts with the body. There are also explanations dealing with clozapines interaction with the serotonin 5HT2 receptors and the glutamate receptors. ... ...hin a week levels will increase with treatment of colazopine.(Naheed & Green, 2000) Andreasen, N.C. (1994). Schizophrenia From Mind to Molecule. Washington, DC American Psychiatric Press.Kalat, J. (2004). Biological Psychology. 8Th edition, Chapter 15.3.Kentridge, B. (1995). S2 Psychopathology Lecture 3 Schizophrenia. Retrieved March 4, 2005. From Http//www.dur.ac.uk/robert.kentridge/ppath3.htmlMann, R. (1996). The Role of Dopamine Receptors in Schizophrenia. Retrieved March 3, 2005, From Stanford University, Chemistry department web site , http//www.chem.csustan.edu/chem44x0/SJBR/Mann.htmNaheed, M., & Green, B. (2000). Focus on Clozapine. Retrieved February 7, 2005. From http//www.priory.com/focus14.htmWaddinton, J.L., & Buckley, P.F. (1996). The neurodevelopmental Basis of Schizophrenia. Austin, TX Landes Co.